产品名称:重组Lon蛋白酶(Lon Protease)
英文名称:Recombinant E. coli Lon Protease
产品规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,表达序列Asn2-Lys784的N端包含His标签。
Lon Protease质量控制:>95%(SEC-HPLC,还原性SDS-PAGE)
Lon Protease制剂:液体
Lon Protease保存:
收到后请置于-20℃以下,可保存长达6个月,避免反复冻融。
关于Lon Protease:
Lon Protease, is a member of the Lon protease family. They are found in archaea, bacteria and eukaryotes. Lon protease is ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins, including some antitoxins. It required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. It degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long and binds to DNA in a double-stranded, site-specific manner. Endogenous substrates include the regulatory proteins RcsA and SulA, the transcriptional activator SoxS, and UmuD. Its overproduction specifically inhibits translation through at least two different pathways, one of them being the YoeB-YefM toxin-antitoxin system.