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Mouse Anti Human Cyclin-Depend

ent Kinase Inhibitor 1B

价格￥1080 - 7500

品牌Prospecbio
产地以色列
货号ant-640
更新日期2025年07月16日

上海经科化学科技有限公司

16 年钻石会员

规格：	5ug	产品价格：	￥1080.0
规格：	20ug	产品价格：	￥2415.0
规格：	100ug	产品价格：	￥7500.0

CATALOGUE NUMBER

ANT-640

SYNONYMS

Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, CDKN1B, KIP1, MEN4, CDKN4, MEN1B.

TYPE

Mouse Anti Human Monoclonal.

INTRODUCTION

Cyclin-dependent kinase inhibitor 1B (CDKN1B) is a member of the Cip/Kip family of cyclin dependent kinase (Cdk) inhibitor proteins. The CDKN1B protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and so controls the cell cycle progression at G1. CDKN1B is often referred to as a cell cycle inhibitor protein since its major function is to stop or slow down the cell division cycle. The degradation of the CDKN1B protein, which is triggered by its CDK dependent phosphorylation and ensuing ubiquitination by SCF complexes, is compulsory for the cellular transition from inactive to the proliferative state.

CLONE

PAT7B9AT.

PHYSICAL APPEARANCE

Sterile filtered colorless solution.

IMMUNOGEN

Anti-human CDKN1B mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CDKN1B amino acids 1-198 purified from E. coli.

IG SUBCLASS

Mouse IgG₁ heavy chain and k light chain.

PURIFICATION METHOD

CDKN1B antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.

FORMULATION

1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.

STORAGE PROCEDURES

For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C.

Prevent freeze thaw cycles.

STABILITY / SHELF LIFE

12 months at -20°C. 1 month at 4°C.

APPLICATIONS

CDKN1B antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

SAFETY DATA SHEET

SDS

USAGE

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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Mouse Anti Human Cyclin-Dependent Kinase Inhibitor 1B

￥1080 - 7500

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