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Mouse Anti Human Cytotoxic T-L

ymphocyte Associated Antigen-4
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  • ￥1080 - 7500
  • Prospecbio
  • 以色列
  • ant-481
  • 2025年07月07日
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    上海经科化学科技有限公司
    16 年钻石会员

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    • 文献和实验
    • 技术资料
    • 保存条件：

      for future use below -18°C

    • 保质期：

      See instructions

    • 英文名：

      CTLA4

    • 库存：

      常规产品有备货

    • 供应商：

      上海经科化学科技有限公司

    • CAS号：

      无

    • 规格：

      5ug/20ug/100ug

    规格：5ug产品价格：￥1080.0
    规格：20ug产品价格：￥2415.0
    规格：100ug产品价格：￥7500.0

    产品细节图片1

    CATALOGUE NUMBER

    ANT-481

    SYNONYMS

    GSE, CD152, IDDM12, CELIAC3, CTLA-4.

    TYPE

    Mouse Anti Human Monoclonal.

    INTRODUCTION

    CTLA-4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

    CLONE

    PAT4F2AT.

    PHYSICAL APPEARANCE

    Sterile filtered colorless solution.

    IMMUNOGEN

    Anti-human CTLA4 mAb, clone PAT4F2AT, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CTLA4 protein 36-161 amino acids purified from E. coli.

    IG SUBCLASS

    Mouse IgG1 heavy chain and Kappa light chain.

    PURIFICATION METHOD

    CTLA4 antibody was purified by protein-A affinity chromatography.

    FORMULATION

    1mg/ml containing PBS, pH-7.4, 10% Glycerol and 0.02% Sodium Azide.

    STORAGE PROCEDURES

    For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. 
    Prevent freeze thaw cycles.

    STABILITY / SHELF LIFE

    12 months at -20°C. 1 month at 4°C.

    APPLICATIONS

    The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:3000. 

    SAFETY DATA SHEET

    SDS

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    该产品被引用文献

    CTLA-4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.

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    Mouse Anti Human Cytotoxic T-Lymphocyte Associated Antigen-4
    ￥1080 - 7500