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- enz-656
- 2026年01月08日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
for future use below -18°C
- 保质期：
See instructions
- 英文名：
bTOP1
- 库存：
常规产品有备货
- 供应商：
上海经科化学科技有限公司
- CAS号：
无
- 规格：
5ug/20ug/1mg
| 规格： | 5ug | 产品价格： | ￥1080.0 |
|---|---|---|---|
| 规格： | 20ug | 产品价格： | ￥2415.0 |
| 规格： | 1mg | 产品价格： | ￥61000.0 |
CATALOGUE NUMBER
ENZ-656
SYNONYMS
INTRODUCTION
DESCRIPTION
Bovine DNA Topoisomerase-I shows multiple bands between 76-109 KDa and is purified from bovine tissues by proprietary chromatographic techniques.
SOURCE
FORMULATION
TOP1 is supplied in 20mM HEPES buffer pH-7.5, 400mM NaCl and 20% glycerol.
IMMUNOLOGICAL FUNCTIONS
1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test (checkerboard analysis of positive/negative samples) and immunodot test with positive/negative samples.
APPLICATIONS
Western blot with anti TOP1 autoantibody positive sample.
COATING CONCENTRATION
PURITY
Greater than 95% as determined by SDS-PAGE.
STABILITY
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
Avoid multiple freeze-thaw cycles.
SAFETY DATA SHEET
SDS
USAGE
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文献和实验Bovine DNA Topoisomerase-I shows multiple bands between 76-109 KDa and is purified from bovine tissues by proprietary chromatographic techniques.
DNA Topoisomerase II-Catalyzed DNA Decatenation
A major role of DNA topoisomerase II in vivo is to catalyze the double-stranded cleavage of DNA, allowing passage of a second DNA duplex through the break. This activity requires adenosine triphosphate (ATP) and is necessary for separating
Purification of DNA Topoisomerase I from Human Placenta
DNA topoisomerase I (topo I) has been firmly established as the molecular target of the camptothecin group of anticancer drugs. These drugs include camptothecin, topotecan, 9-amino-camptothecin, and irinotecan
Assaying DNA Topoisomerase I Relaxation Activity
Type I topoisomerases catalyze topological changes in duplex DNA by reversibly nicking one strand, whereas type II enzymes catalyze the transient breakage of both strands simultaneously. The type I enzymes alter the linking number
技术资料