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Recombinant Human 6-Pyruvoylte

trahydropterin Synthase
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  • ¥1080 - 35500
  • Prospecbio
  • 以色列
  • enz-471
  • 2026年01月08日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      for future use below -18°C

    • 保质期

      See instructions

    • 英文名

      PTPS

    • 库存

      常规产品有备货

    • 供应商

      上海经科化学科技有限公司

    • CAS号

    • 规格

      5ug/25ug/1mg

    规格:5ug产品价格:¥1080.0
    规格:25ug产品价格:¥2415.0
    规格:1mg产品价格:¥35500.0

    产品细节图片1

    CATALOGUE NUMBER

    ENZ-471

    SYNONYMS

    PTP Synthase, 6-Pyruvoyl Tetrahydropterin Synthase, PTPS, PTS, FLJ97081.

    INTRODUCTION

    6-PyruvoylTetrahydropterin Synthase is part of the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. 6-PyruvoylTetrahydropterin Synthase catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, is a necessary cofactor and regulator of a range of enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in 6-PyruvoylTetrahydropterin Synthase gene result in hyperphenylalaninemia.

    DESCRIPTION

    6-PyruvoylTetrahydropterin Synthase Human Recombinant produced in e.coli is a single, non-glycosylated polypeptide chain containing 165 amino acids (1-145) and having a molecular mass of 18.5kDa. 6-PyruvoylTetrahydropterin Synthase is fused to a 20 amino acid His Tag at N-terminus and purified using conventional chromatography techniques.

    SOURCE

    Escherichia Coli.

    PHYSICAL APPEARANCE

    Sterile Filtered colorless solution.

    FORMULATION

    6-PyruvoylTetrahydropterin Synthase is formulated in 20mM Tris-HCl buffer pH-8, 1mM DTT and 20% glycerol.

    STABILITY

    Store at 4°C if entire vial will be used within 2-4 weeks. 
    Store, frozen at -20°C for longer periods of time. 
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). 
    Avoid multiple freeze-thaw cycles.

    PURITY

    Greater than 95.0% as determined by Analysis by SDS-PAGE.

    AMINO ACID SEQUENCE

    MG./S-SHHHHHH SSGLVPRGSH MSTEGGGRRC QAQVSRRISF SASHRLYSKF LSDEENLKLF GKCNNPNGHG HNYKVVVTVH GEIDPATGMV MNLADLKKYM EEAIMQPLDH KNLDMDVPYF ADVVSTTENV AVYIWDNLQK VLPVGVLYKV KVYETDNNIV VYKGE.

    SAFETY DATA SHEET

    SDS

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
     

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    图标文献和实验
    该产品被引用文献

    6-PyruvoylTetrahydropterin Synthase Human Recombinant produced in e.coli is a single, non-glycosylated polypeptide chain containing 165 amino acids (1-145) and having a molecular mass of 18.5kDa. 6-PyruvoylTetrahydropterin Synthase is fused to a 20 amino acid His Tag at N-terminus and purified using conventional chromatography techniques.

    相关实验
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      To date three distinct isoforms of nitric oxide synthase (NOS) have been identified. Two isoforms are considered to be expressed constitutively—neu-ronal NOS (nNOS; type I NOS) and endothelial NOS (eNOS; type III NOS). The third isoform

    • Cloning and Expression of Human Inducible Nitric Oxide Synthase

      NO synthase (NOS) pathway was first characterized and cloned in murine macrophages (1 –3 ). Activation with lipopolysaccharide (LPS) and interferon-γ (IFN-γ) was uniformly used in these studies to increase inducible (i) NOS expression and improve cloning

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    文献支持
    Recombinant Human 6-Pyruvoyltetrahydropterin Synthase
    ¥1080 - 35500