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- chm-267
- 2025年12月28日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
for future use below -18°C
- 保质期：
See instructions
- 英文名：
rENA 78
- 库存：
常规产品有备货
- 供应商：
上海经科化学科技有限公司
- CAS号：
无
- 规格：
5ug/20ug/1mg
| 规格： | 5ug | 产品价格： | ￥1080.0 |
|---|---|---|---|
| 规格： | 20ug | 产品价格： | ￥2415.0 |
| 规格： | 1mg | 产品价格： | ￥45885.0 |
CATALOGUE NUMBER
CHM-267
SYNONYMS
INTRODUCTION
Chemokine (C-X-C motif) ligand 5 (CXCL5) is a small cytokine belonging to the CXC chemokine family that is also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78). It is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. Expression of CXCL5 has also been observed in eosinophils. This chemokine stimulates the chemotaxis of neutrophils possesses angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2. The gene for CXCL5 is encoded on four exons and is located on human chromosome 4 amongst several other CXC chemokine genes. CXCL5 has been implicated in connective tissue remodelling.
DESCRIPTION
non-glycosylated, polypeptide chain containing 93 amino acids and having a molecular mass of 10.0kDa.
The CXCL5 is purified by proprietary chromatographic techniques.
SOURCE
PHYSICAL APPEARANCE
FORMULATION
SOLUBILITY
STABILITY
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
PURITY
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
AMINO ACID SEQUENCE
BIOLOGICAL ACTIVITY
SAFETY DATA SHEET
SDS
USAGE
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文献和实验Epithelial Neutrophil-Activating Protein 78 Rat Recombinant produced in E.Coli is a single,
non-glycosylated, polypeptide chain containing 93 amino acids and having a molecular mass of 10.0kDa.
The CXCL5 is purified by proprietary chromatographic techniques.
目前肝癌(HCC)是世界上主要的几大高发癌症之一，其发病率和死亡率近年来呈上升趋势，并且术后的复发和转移率很高，但HCC病变的分子机理和涉及的信号通路尚不明确，也有几个用于评估复发和转移的分子标示物被提及，但目前还未用于临床检测中。炎症作为癌症的特征之一，HCC主要发生于肝炎，中国人主要是发病于B型肝炎，欧美则主要是C型肝炎。趋化因子与炎症的发生密切相关，并通过一些信号通路促进肿瘤发生。近年研究发现趋化因子CXCL5(epithelial neutrophil-activating
Evaluating Modulators of “Regulator of G‐protein Signaling” (RGS) Proteins
4 ) Recombinant RGS4 protein (purified as in Zielinski et al., ; also see protocol 5 ) Black, 384‐well assay plates with a nonbinding
secondary antibody review -- data from 99 publications
epithelial Caco2/bbe cells Bio-Rad 10 rhodamine immunocytochemistry 1:100 detect phospho-CREB in human colonic epithelial Caco2/bbe cells Bio-Rad 11 goat IgG FITC immunohistochemistry 1:40 detect ameloblastin in mouse postnatal mandibular molars
技术资料