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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
for future use below -18°C
- 保质期:
See instructions
- 英文名:
GLP1
- 库存:
常规产品有备货
- 供应商:
上海经科化学科技有限公司
- CAS号:
无
- 规格:
1mg/5mg/100mg
| 规格: | 1mg | 产品价格: | ¥1080.0 |
|---|---|---|---|
| 规格: | 5mg | 产品价格: | ¥2415.0 |
| 规格: | 100mg | 产品价格: | ¥29500.0 |
CATALOGUE NUMBER
HOR-284
SYNONYMS
INTRODUCTION
GLP-1 secretion by L cells is dependent on the presence of nutrients in the lumen of the small intestine. The secretagogues (agents that causes or stimulates secretion) of this hormone include major nutrients like carbohydrate, proteinand lipid. Once in the circulation, GLP-1 has a half life of less than 2 minutes, due to rapid degradation by the enzyme dipeptidyl peptidase-4.
GLP-1 possesses several physiological properties that make it a subject of intensive investigation as a potential treatment of diabetes mellitus. The known physiological functions of GLP-1 include: Increases insulin secretion from the pancreas in a glucose-dependent manner, decreases glucagon secretion from the pancreas, increases beta cells mass and insulin gene expression, inhibits acid secretion and gastric emptying in the stomach, decreases food intake by increasing satiety.
DESCRIPTION
The GLP-1 is purified by proprietary chromatographic techniques.
PHYSICAL APPEARANCE
FORMULATION
SOLUBILITY
It is recommended to reconstitute the lyophilized Glucagon Like Peptide-1 in sterile H2O at 0.5mg/ml, which can then be further diluted to other aqueous solutions.
STABILITY
Please prevent freeze-thaw cycles.
PURITY
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文献和实验Title: Synthetic (+)?antroquinonol exhibits dual actions against insulin resistance by triggering AMP kinase and inhibiting dipeptidyl peptidase IV activities
Publications: British journal of pharmacology 172.1 (2015): 38-49.
三句话读懂一篇 CNS:橙子可甜可酸的原因;吃红肉促进结直肠癌发生的分子机制...
论文 Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor,首次报道了 Compound 2 结合 GLP-1R 的三个高分辨率冷冻电镜结构,突破技术瓶颈, 揭示了该受体变构激动调节的分子机制,为拓展受体药理学内涵和相关药物发现提供了重要的结构基础。 图 10. 来源 Nature Communications 本周推荐:三句话读懂一篇 CNS:男性的大脑和睾丸相似;父亲熬夜,影响
【分享】Human press METHODS IN MOLECULAR BIOLOGY
and Protocols, 1st Ed., Edited by L.C. Javios, 1994 35. Peptide Synthesis Protocols, Edited by Penning- ton, Michael W., 1994 36. Peptide Analysis Protocols Edited by Dunn, Ben M., 1994 37. In Vitro Transcription and Translation Protoc- ols Edited
Access Guide to Human Proteinpedia
, protein/peptide microarrays, fluorescent micrographs, and western blots, ensures quality of proteomic data assimilated in Human Proteinpedia. Many of the protein annotations submitted to Human Proteinpedia have also been made available to the scientific
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