- ￥816 - 2100
- Elabscience
- E-AB-F1107E
- 湖北武汉
- 2025年07月12日
- FCM
- Rat
- Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
APC Anti-Mouse CD115/CSF-1R Antibody流式抗体[AFS98]_货号:E-AB-F1107E
- 抗体英文名：
APC Anti-Mouse CD115/CSF-1R Antibody[AFS98]_货号:E-AB-F1107E
- 应用范围：
FCM
- 宿主：
Rat
- 适应物种：
Mouse
- 保质期：
12个月
- 目录编号：
E-AB-F1107E
- 级别：
科研
- 库存：
999
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 标记物：
APC
- 克隆性：
Monoclonal
- 保存条件：
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
- 形态：
液体
- 亚型：
Rat IgG2a, κ
- 规格：
100Tests/50Tests/100Tests×2
| 规格： | 100Tests | 产品价格： | ￥1380.0 |
|---|---|---|---|
| 规格： | 50Tests | 产品价格： | ￥816.0 |
| 规格： | 100Tests×2 | 产品价格： | ￥2100.0 |
货号：E-AB-F1107E
| Background |
CSF-1R, also known as CD115 and M-CSFR, is a single-pass type I membrane protein and member of the platelet-derived growth factor receptor family. This c-fms (Fms proto-oncogene) gene product's natural ligands include M-CSF and IL-34. Structural studies of CD115 have described an Ig-like extracellular domain, a transmembrane domain, an intracellular juxtamembrane domain, a split tyrosine kinase domain, and a C-terminal tail receptor. Receptor activation induces homodimerization in addition to phosphorylation and ubiquitination of intracellular residues. CD115 directly influences tissue macrophage and osteoclast differentiation and proliferation. It is expressed on monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, and osteoclasts.
|
| Alternate Names |
Macrophage colony-stimulating factor 1 receptor;CSF-1 receptor (EC:2.7.10.1);CSF-1-R;CSF-1R;M-CSF-R;Proto-oncogene c-Fms;CD115;Csf1r;Csfmr;Fms;
|
| Swissprot |
P09581
|
| Gene ID |
12978
|
| Clone No |
AFS98
|
| Host |
Rat
|
| Reactivity |
Mouse
|
| Application |
FCM
|
| Isotype |
Rat IgG2a, κ
|
| Isotype Control |
APC Rat IgG2a, κ Isotype Control[2A3]
|
| Conjugation |
APC
|
| Conjugation Information |
APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
|
| Storage Buffer |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
|
| Storage |
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
|
| Expiration date |
12个月
|
| Shipping |
冰袋
|
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（Antigen-presenting Cells, APC）。粒细胞主要分为三种：中性粒细胞、嗜酸性粒细胞和嗜碱性粒细胞。其中，中性粒细胞在哺乳动物血液白细胞中所占比例最大，而嗜酸性粒细胞和嗜碱性粒细胞数量稀少，均不超过白细胞数量的 1%，在免疫学研究中的关注相对较少。 血液中的单核细胞对机体发生的损伤和炎症响应迅速，通常在 8~12 小时就能进入病灶部位。小鼠血液中，单核细胞以典型的 CD11b（Cat#E-AB-F1081）和 CD115（Cat#E-AB-F1107）双阳特征出现，而在人的外周血中
Isotype-specific immunostaining with mouse primary antibodies on mouse tissue
) Briefly, substitute your anti H+L pan-reactive secondary antibody with an anti-isotype heavy chain specific secondary. Be aware of possible odd crossreactivties (e.g. many goat anti mouse IgG 1 heavy chain do stain rat IgG 2a
Intracellular Cytokine Staining Protocol
F4/80 CI:A3-1 n/a not on blood monocytes CD115/M-CSFR AFS98 14-1152 CD
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