Human prostate specific antige

产品信息：Human Prostate-specific antigen (PSA) is a single chain glycoprotein with Mol. Wt. Of 34 kDa containing 7% carbohydrates. It is uniquely associated with prostate tissue and presents in both normal and cancerous prostatic tissue, prostatic fluid and seminal plasma (1). PSA is not present in any of the normal tissue obtained from men nor is it produced by cancers of the lung, colon, rectum, stomach, breast, pancreas or thyroid (2). Elevated serum PSA concentration have been reported in patient with prostate cancer, benign prostatic hypertrophy, or inflammatory tissues, but not in apparently healthy women with cancer (3). PSA levels correlate with the stage of disease and response to treatment in-patients with prostatic cancer (4-7). Therefore sequential measurements of PSA concentration can be an important tool in monitoring patients with prostatic cancer and in determining the potential and effectiveness of surgery of other therapies.