重组人GCDH(线粒体戊二酰辅酶A脱氢酶)

特别提示：包括重组人GCDH(线粒体戊二酰辅酶A脱氢酶)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人GCDH(线粒体戊二酰辅酶A脱氢酶)
英文名称：Recombinant Human Glutaryl-CoA Dehydrogenase, Mitochondrial
产品货号：JN1026
产品规格：10μg|50μg|500μg|1mg

本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Arg45-Lys438在N端含有His标签。

GCDH质量控制：＞95%(还原性SDS-PAGE)

GCDH制剂：液体

GCDH保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于GCDH：
Glutaryl-CoA Dehydrogenase Mitochondrial (GCDH) is an enzyme that acts upon glutaryl-coenzyme A, creating crotonyl-coenzyme A. It plays a role in the metabolism of lysine, hydroxylysine and tryptophan. It uses electron transfer flavoprotein as its electron acceptor. Isoform Short is inactive Glutaryl-CoA and electron-transfer flavoprotein to (E)-but-2-enoyl-CoA, CO2 and reduced electron-transfer flavoprotein. A defect in this enzyme is associated with neurological condition glutaric acidemia type 1 and cause a progressive form of early-onset generalized dystonia.

除了重组人GCDH(线粒体戊二酰辅酶A脱氢酶),，我公司还供应以下相关产品：



名称：重组人β-NGF(β神经生长因子)
货号：JN0261
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的Ser122-Arg239表达纯化而来。

beta-NGF质量控制：＞95%(还原性SDS-PAGE)。

beta-NGF制剂：冻干品

beta-NGF保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。

beta-NGF复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。

关于beta-NGF：
Human β-Nerve Growth Factor (β-NGF) was initially isolated in the mouse submandibular gland. It is composed of three non-covalently linked subunits α, β, and γ; it exhibits all the biological activities ascribed to NGF. It is structurally related to BDNF, NT-3 and NT-4 and belongs to the cysteine-knot family of growth factors that assume stable dimeric structures. Β-NGF is a neurotrophic factor that signals through its receptor β-NGF, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. Β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. These results suggest that β-NGF is a pleiotropic cytokine, which in addition to its neurotropic activities may have an important role in the regulation of the immune system. Human β-NGF shares 90% sequence similarity with mouse protein and shows cross-species reactivity.