MMP2 mouse monoclonal antibody

gene_symbol：MMP2
predicted_size：70.9 kDa
Uniprot ID：P8253
description：MMP2 mouse monoclonal antibody, clone OTI4A11 (formerly 4A11)
clonality：Monoclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
immunogen：Human recombinant protein fragment corresponding to amino acids 228-507 of human MMP2(NP_004521) produced in E.coli.
recommended_dilution：WB 1:2000, IHC 1:150
predicted_size：70.9 kDa
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
host_species：Mouse
applications：IHC, WB
reactivities：Human, Mouse, Rat