Rabbit Polyclonal Anti-SAMHD1

gene_symbol：SAMHD1
predicted_size：Predicted: 69 kDa
Uniprot ID：Q9Y3Z3
description：Rabbit Polyclonal Anti-SAMHD1 (phospho Thr592) Antibody
clonality：Polyclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：The SAM domain and HD domain 1 (SAMHD1) protein is upregulated in response to viral infection and is thought to play a role in innate immunity (1). SAMHD1 blocks the infection of HIV-1 and SIVdeltaVpx before reverse transcription in macrophages and dendritic cells (2), and this restriction is regulated by phosphorylation of SAMHD1 (3). Mutations in this gene have been associated with Aicardi-Goutieres syndrome (1).
immunogen：Phospho-SAMHD1 antibody was raised against a phosphorylated 18 amino acid peptide near the carboxy terminus of human Phospho-SAMHD1 surrounding T592.
recommended_dilution：WB: at 0.5-1µg/ml.IHC starting at 2.5µg/mL. IF start at 20µg/mL.
predicted_size：Predicted: 69 kDa
buffer：SAMHD1 (phospho Thr592) antibody is supplied in PBS containing 0.02% sodium azide.
host_species：Rabbit
applications：IF, IHC, WB
reactivities：Human, Mouse