- ￥3000
- GeneTex
- 美国
- GTX23079
- 2025年07月08日
- ELISA,WB,IHC等
- rabbit/mouse
- human/mouse/rat等
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
请参考说明书
- 亚型：
请参考说明书
- 形态：
液体
- 保存条件：
Aliquot and store at -20ºC
- 克隆性：
请参考说明书
- 标记物：
请参考说明书
- 适应物种：
human/mouse/rat等
- 宿主：
rabbit/mouse
- 应用范围：
ELISA,WB,IHC等
- 浓度：
请参考说明书
- 靶点：
请参考说明书
- 抗体英文名：
pS2 antibody [pS2.1]
- 抗体名：
pS2 antibody [pS2.1]
- 规格：
500μl
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文献和实验The Phosphorylation of Presenilin Proteins
The phosphorylation of presenilin (PS) proteins was initially analyzed in cultured cells overexpressing the respective proteins. These studies revealed that the homologous PS proteins are differentially phosphorylated in vivo. Fulllength PS2
Normal Proteolytic Processing of the Presenilins
The majority of familial Alzheimer’s disease (AD) cases are linked to mutations of the presenilin 1 and 2 (PS1, PS2 ) genes on chromosomes 14 and 1, respectively (1 -3 ). PS1 and PS2 are about 67% identical in amino acid sequence. Based
Interaction of the Presenilins with the Amyloid Precursor Protein (APP)
The genes encoding presenilin-1 (PS1 ) and presenilin-2 (PS2 ) were identified as the genes that harbour mutations that cause more than 60% of early onset familial Alzheimer’s disease cases (FAD) (1 -3 ). So far, more than 40 missense mutations
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