GnRH (GNRH1) (11-60) rabbit po

gene_symbol：GNRH1
predicted_size：~ 11 kDa
Uniprot ID：P1148
description：GnRH (GNRH1) (11-60) rabbit polyclonal antibody, Aff - Purified
clonality：Polyclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：GnRH is produced by hypothalamic neurons and secreted in a pulsatile manner into the capillary plexus of the median eminence. GnRH affects the release of lutenizing hormone and follicle stimulating hormone from gonadotropic cells in the anterior pituitary. In addition to hypothalamic GnRH (GnRH I), a second GnRH form (GnRH II) functions primarily in the midbrain. GnRH is xpressed in the acrosomal region of human sperm and in the anterior pituitary tissue and cancer cells. Unlike GnRH I, GnRH II is highly expressed outside the brain, particularly in the kidney, bone marrow and prostate, suggesting that it may have multiple functions. GnRH binds to a specific G protein-coupled receptor in the pituitary to regulate synthesis and secretion of gonadotropins.
immunogen：Synthetic peptide corresponding to amino acids 11-60 of Human GnRH I.
recommended_dilution：Western blot: 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
predicted_size：~ 11 kDa
buffer：PBS, pH 7.2; State: Aff - Purified; State: Liquid purified Ig fraction (> 95% by SDS-PAGE); Preservative: 0.05% Sodium Azide
host_species：Rabbit
applications：IHC, WB
reactivities：Human, Mouse, Rat