- ￥5300
- GeneTex
- 美国
- GTX13549
- 2025年07月05日
- WB, FACS, Blocking, IHC, in vivo
- Mouse
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant full length protein (Human).
- 亚型：
IgG1
- 形态：
Liquid
- 保存条件：
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
12 months from the shipping date of the product.
- 抗原来源：
Human
- 目录编号：
GTX13549
- 级别：
Primary Antibodies
- 库存：
Available
- 供应商：
GeneTex
- 宿主：
Mouse
- 应用范围：
WB, FACS, Blocking, IHC, in vivo
- 浓度：
1 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点：
This antibody has been demonstrated to block the apoptotic activity of other anti-CD95 antibodies that are known to induce apoptosis.
- 抗体英文名：
Fas antibody [ZB4]
- 抗体名：
Fas 抗体 [ZB4]
- 规格：
50 μg
Western blot analysis of human Fas expression in human Fas transfected cells
Lane 1: anti-human Fas (ZB4)
Lane 2: anti-human Fas (UB2)
Lane 3: anti-human Fas (CH11).
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文献和实验Yang T et al., J Exp Clin Cancer Res 2015 (PMID:25887782)
Lin KH et al., Cardiovasc Res 2009 (PMID:19423619)
Dabrowska A et al., J Immunol 2008 (PMID:19050264)
Zhang X et al., J Extracell Vesicles 2022 (PMID:36856683)
Kawasaki N et al., Mol Biol Rep 2022 (PMID:35218445)
Tan X et al., Transpl Int 2021 (PMID:33725365)
Dou R et al., Mol Immunol 2018 (PMID:29783159)
an important role in regulation of the immune system. In the method described, hepatoma MH134 (Fas− and FasL− ) is transfected with murine Fas and FasL cDNA. A single administration of monoclonal anti-Fas antibody efficiently suppresses the growth of F6b (MH134
and inhibit concomitant progressive tissue destruction. Of particular interest in this respect is the use of the so-called single-chain fragments of variable region (scFv) antibody fragments for the targeted reactivation of Fas-dependent activation-induced
cell membrane-associated molecules that transduce apoptotic signals, e.g., Fas Ligand (FasL) or TRAIL (reviewed in refs. 1 ,2 ). Target cell recognition by NK cells occurs via either of two ways: (1) receptors capable of binding molecules
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