CCR2 mouse monoclonal antibody

gene_symbol：CCR2
predicted_size：null
Uniprot ID：P41597
description：CCR2 mouse monoclonal antibody, clone 7A7, Purified
clonality：Monoclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：CCR2B is a 374 amino acid protein that belongs to the G - protein coupled receptor 1 family with seven transmembrane domains. It mediates the chemotactic properties of monocyte chemoattractant protein 1 (MCP - 1) which is secreted by endothelial and epithelial cells, vascular smooth muscle and hematopoietic cells. MCP - 1 is a potent chemoattractant for monocytes and lymphocytes. It is responsible for monocyte infiltration in a variety of chronic inflammatory diseases.
immunogen：DNA vaccine
recommended_dilution：Immunohistochemistry on paraffin sections: 10-20 µg/ml (1/40-1/20). Pretreatment with proteinase K required. Immunohistochemistry on frozen tissues: 4-8 µg/ml (1/100 - 1/50). Human tonsil is suggested as positive control tissue.
predicted_size：null
buffer：Phosphate buffered saline pH 7.2 (PBS); State: Purified; State: Lyophilized affinity purified Ig fraction; Stabilizer: 5 mg/ml BSA; Preservative: 0.1% Kathon
host_species：Mouse
applications：IHC
reactivities：Human