Lyve1 rabbit polyclonal antibo

gene_symbol：Lyve1
predicted_size：null
Uniprot ID：Q8BHC
description：Lyve1 rabbit polyclonal antibody, Aff - Purified
clonality：Polyclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
immunogen：Highly pure (> 95%) recombinant Mouse soluble LYVE-1 (Ala24-Gly228) produced in insect cells (Cat.-No DA3524).
recommended_dilution：ELISA: 1-15 µg/ml. Western blot: 2-5 µg/ml. FACS analysis: 3-10 µg/ml.  Immunofluorescence. Immunohistochemistry on Paraffin and Frozen Sections: 0.25-4 µg/ml.
predicted_size：null
buffer：PBS, pH 7.4, without preservatives or stabilizers; State: Aff - Purified; State: Lyophilized purified IgG fraction
host_species：Rabbit
applications：ELISA, FC, IF, IHC, WB
reactivities：Mouse, Rat