重组人补体因子H(CFH)

特别提示：包括重组人补体因子H(CFH)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人补体因子H(CFH)
英文名称：Recombinant Human Complement factor H
产品货号：JN1221
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Glu19-Leu449在C端含有His标签。

CFH质量控制：＞95%(还原性SDS-PAGE)

CFH制剂：液体

CFH保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于CFH：
Complement Factor H (CFH) is a secreted protein which is a member of the regulators of complement activation family and is a complement control protein. It is expressed by the liver and secreted in plasma. Its principal function is to regulate the Alternative Pathway of the complement system, ensuring that the complement system is directed towards pathogens or other dangerous material and does not damage host tissue. Factor H regulates complement activation on self cells and surfaces by possessing both cofactor activity for the Factor I mediated C3b cleavage, and decay accelerating activity against the alternative pathway C3-convertase, C3bBb. Factor H exerts its protective action on self cells and self surfaces but not on the surfaces of bacteria or viruses, because it binds to glycosaminoglycans (GAGs) that are generally present on host cells but not, normally, on pathogen surfaces.

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