Annexin V-FITC kit

Annexin V is a phospholipid binding protein that belongs to the Annexin family. In the presence of calcium ions it exhibits a high affinity for binding selectively to phosphatidylserine (PS). The appearance of PS on the cell surface is one of the early structural changes in cells undergoing apoptosis. Annexin V displays very low affinity for other phospholipid species like phosphatidylethanolamine, sphingomyelin and phosphatidyl-choline, making it an ideal reagent for detecting apoptosis.