产品英文名称: Recombinant Human TGFB1-Induced Anti-Apoptotic Factor 1
英文简称: TIAF1
中文名称: 重组人TGFB1诱导抗凋亡因子1
背景资料: TGFB1-induced anti-apoptotic factor 1 (TIAF1) hinders the cytotoxic e大肠杆菌中重组表达ects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1. The TIAF1 protein is involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation. TIAF1 is not detected in normal kidney and liver. TIAF1 is up-regulated in chronic and acute allograft rejection: expressed in the inflammatory infiltrate and in tubular epithelial cells.
产品描述: TIAF1 Human Recombinant produced in E. coli is a single polypeptide chain containing 152 amino acids (1-115) and having a molecular mass of 16.6 kDa.TIAF1 is fused to a 37 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
来源宿主: 大肠杆菌中重组表达