重组人不均一核核糖核蛋白A1

产品英文名称：
Recombinant Human Heterogeneous Nuclear Ribonucleoprotein A1

英文简称:
HNRNPA1

中文名称:
重组人不均一核核糖核蛋白A1

背景资料:
Heterogeneous nuclear ribonucleoprotein A1 （HNRNPA1） is a member of the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins （hnRNPs）. HNRNPA1 is involved in the packing of pre-mRNA into hnRNP particles， transport of poly（A） mRNA from the nucleus to the cytoplasm and may control splice site selection. The HNRNPA1 protein may also have a role in HCV RNA replication. In addition， HNRNPA1 is believed to have a key role in the formation of specific myometrial protein species in parturition. The hnRNP proteins have distinctive nucleic acid binding properties. HNRNPA1 has 2 repeats of quasi-RRM domains that bind to RNAs. HNRNPA1 is one of the most copious core proteins of hnRNP complexes and it is restricted to the nucleoplasm. The HNRNPA1 protein， along with other hnRNP proteins， is exported from the nucleus， most likely bound to mRNA， and is immediately re-imported. The M9 domain of HNRNPA1 functions as both a nuclear localization and nuclear export signal.

产品描述:
HNRNPA1 Human Recombinant produced in E.Coli is a single， non-glycosylated polypeptide chain containing 343 amino acids （1-320 a.a.） and having a molecular mass of 36.6kDa. HNRNPA1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
来源宿主:
大肠杆菌中重组表达

序列:
MGSSHHHHHH SSGLVPRGSH MGSMSKSESP KEPEQLRKLF IGGLSFETTD ESLRSHFEQW GTLTDCVVMR DPNTKRSRGF GFVTYATVEE VDAAMNARPH KVDGRVVEPK RAVSREDSQR PGAHLTVKKI FVGGIKEDTE EHHLRDYFEQ YGKIEVIEIM TDRGSGKKRG FAFVTFDDHD SVDKIVIQKY HTVNGHNCEV RKALSKQEMA SASSSQRGRS GSGNFGGGRG GGFGGNDNFG RGGNFSGRGG FGGSRGGGGY GGSGDGYNGF GNDGSNFGGG GSYNDFGNYN NQSSNFGPMK GGNFGGRSSG PYGGGGQYFA KPRNQGGYGG SSSSSSYGSG RRF.

溶解建议:
提供的重组人不均一核核糖核蛋白A1产品形式为经无菌过滤处理的无色溶液.

保存建议：
重组人不均一核核糖核蛋白A1产品在4℃保存请2 - 4周内将使用；-20℃可长期保存.产品若长期保存，建议添加载体蛋白（0.1% HSA或BSA）.避免反复冻融.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。
上海淳麦生物为ProSpec国内代理销售经销商，详细的产品信息请和我们联系：免费热线：4006815880 微信电话 13770640776