人高密度脂蛋白

产品英文名称：
Human High Density Lipoprotein

英文简称:
HDL

中文名称:
人高密度脂蛋白

背景资料:
HDL is a complex of lipids and proteins in approximately equal amounts that functions as a transporter of cholesterol in the blood. HDL is the smallest of the lipoprotein particles； it’s the densest because it contains the highest proportion of protein. The liver synthesizes these lipoproteins as complexes of apolipoproteins and phospholipid， which bear a resemblance to cholesterol-frHuman High Density Lipoprotein （HDL） produced in Human plasma. flattened spherical lipoprotein particles. They pick up cholesterol； carry it internally， from cells by interaction with the ATP Binding Cassette Transporter A1. Lecithin-cholesterol acyltransferase （plasma enzyme） converts the frHuman High Density Lipoprotein （HDL） produced in Human plasma. cholesterol into cholesteryl ester （a more hydrophobic form of cholesterol） which is then sequestered into the core of the lipoprotein particle ultimately making the newly synthesized HDL spherical. They increase in size as they pass through the bloodstream and integrate more cholesterol and phospholipid molecules from cells and other lipoproteins， for instance by the interaction with the ABCG1 transporter and the phospholipid transport protein. HDL transports their cholesterol generally to the liver or steroidogenic organs such as adrenals， ovary and testes by direct and indirect pathways. The release of HDL cholesterol to adrenals， ovaries and testes is important for the synthesis of steroid hormones. Since the triglycerides are not stable in HDL， they’re degraded by hepatic lipase in order that finally small HDL particles are left which resume the uptake of cholesterol from cells. The cholesterol supplied to the liver is excreted into the bile and consequently intestine either directly or indirectly after conversion into bile acids. High levels of HDL are associated with a decreased risk of atherosclerosis and coronary heart disease.

产品描述:
Human High Density Lipoprotein （HDL） produced in Human plasma.
来源宿主:
人血浆中提取纯化

序列:


溶解建议:
Sterile Filtered clear solution.

保存建议：
Human HDL although stable at 4℃ for 1 week， should be stored desiccated below -15℃. （short term i.e. < 3 months） and below -70℃ for long term.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。
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