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- 详细信息
- 技术资料
- 保存条件:
2-8度
- 保质期:
1年
- 英文名:
SAT1
- 库存:
999
- 供应商:
上海淳麦
- 规格:
/5ug/20ug/1mg
产品英文名称:
Recombinant Human Spermidine/Spermine N1-Acetyltransferase 1
英文简称:
SAT1
中文名称:
重组人精脒/精胺乙酰转移酶1
背景资料:
SAT-1 is a member the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. SAT1 catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Therefore, SAT-1’s role is essential in polyamine homoeostasis, given that acetylated products are either excreted from the cell or oxidized by acetylpolyamine oxidase. Increased SAT1 activity causes variety of other e大肠杆菌中重组表达ects which include pancreatic cells death, obstruction of regenerative tissue growth, behavioral changes, keratosis follicularis spinulosa decalvans(KFSD), and hair loss. Defects in the SAT1 gene are linked to KFSD(keratosis follicularis spinulosa decalvans), which is a rare X-linked disorder a大肠杆菌中重组表达ecting the skin and the eye. The KFSD a大肠杆菌中重组表达ected men show thickening of the skin of the neck, ears, and extremities, particularly the palms and soles, loss of eyebrows, eyelashes and beard, thickening of the eyelids with blepharitis and ectropion, and corneal degeneration. Even though the majority of the a大肠杆菌中重组表达ected families are compatible with an X-linked inheritance, KFSD are found to be clinically and genetically heterogeneous.
产品描述:
人精脒/精胺乙酰转移酶1重组蛋白是在大肠杆菌中重组表达的,是一条单链、非糖基化的多肽链,包含有191个氨基酸(1-171 a.a.),分子量为22.1kDa.该人精脒/精胺乙酰转移酶1重组蛋白的N末端融合了一个20个氨基酸的His标签,该蛋白最终由标准的色谱技术纯化出.
来源宿主:
大肠杆菌中重组表达
序列:
MGSSHHHHHH SSGLVPRGSH MAKFVIRPAT AADCSDILRL IKELAKYEYM EEQVILTEKD LLEDGFGEHP FYHCLVAEVP KEHWTPEGHS IVGFAMYYFT YDPWIGKLLY LEDFFVMSDY RGFGIGSEIL KNLSQVAMRC RCSSMHFLVA EWNEPSINFY KRRGASDLSS EEGWRLFKID KEYLLKMATE E.
溶解建议:
提供的人精脒/精胺乙酰转移酶1(SAT1)产品为过滤灭菌的无色溶液;其中人精脒/精胺乙酰转移酶1(SAT1)产品溶解于20mM Tris-HCl缓冲液(pH 8.0),10%甘油溶液中.
保存建议:
人精脒/精胺乙酰转移酶1(SAT1)溶液可以在4℃冷藏保存4周;如果想延长保存时间,建议分装(加载体蛋白如0.1% HSA或 BSA)后置于-18℃冻存.请避免反复冻融.
其他简介:
ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列,专注于蛋白(重组及合成)生产研发,其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子,生长因子,激素,信号蛋白,病毒抗原等近800种重组蛋白和100多种抗体,是世界上提供蛋白品种最多的公司之一,领先的生产工艺和规模使其可以提供毫克到克级蛋白,价格优于同类公司。绝大部分产品是天然成熟型蛋白,而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液,ProSpec-Tany绝大部分产品没有添加保护剂或盐,这就对工艺提出了更高的要求。同时,ProSpec-Tany绝大部分产品为冻干粉,因此易于运输和保存。
上海淳麦生物为ProSpec国内代理销售经销商,详细的产品信息请和我们联系:免费热线:4006815880 微信电话 13770640776
Recombinant Human Spermidine/Spermine N1-Acetyltransferase 1
英文简称:
SAT1
中文名称:
重组人精脒/精胺乙酰转移酶1
背景资料:
SAT-1 is a member the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. SAT1 catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Therefore, SAT-1’s role is essential in polyamine homoeostasis, given that acetylated products are either excreted from the cell or oxidized by acetylpolyamine oxidase. Increased SAT1 activity causes variety of other e大肠杆菌中重组表达ects which include pancreatic cells death, obstruction of regenerative tissue growth, behavioral changes, keratosis follicularis spinulosa decalvans(KFSD), and hair loss. Defects in the SAT1 gene are linked to KFSD(keratosis follicularis spinulosa decalvans), which is a rare X-linked disorder a大肠杆菌中重组表达ecting the skin and the eye. The KFSD a大肠杆菌中重组表达ected men show thickening of the skin of the neck, ears, and extremities, particularly the palms and soles, loss of eyebrows, eyelashes and beard, thickening of the eyelids with blepharitis and ectropion, and corneal degeneration. Even though the majority of the a大肠杆菌中重组表达ected families are compatible with an X-linked inheritance, KFSD are found to be clinically and genetically heterogeneous.
产品描述:
人精脒/精胺乙酰转移酶1重组蛋白是在大肠杆菌中重组表达的,是一条单链、非糖基化的多肽链,包含有191个氨基酸(1-171 a.a.),分子量为22.1kDa.该人精脒/精胺乙酰转移酶1重组蛋白的N末端融合了一个20个氨基酸的His标签,该蛋白最终由标准的色谱技术纯化出.
来源宿主:
大肠杆菌中重组表达
序列:
MGSSHHHHHH SSGLVPRGSH MAKFVIRPAT AADCSDILRL IKELAKYEYM EEQVILTEKD LLEDGFGEHP FYHCLVAEVP KEHWTPEGHS IVGFAMYYFT YDPWIGKLLY LEDFFVMSDY RGFGIGSEIL KNLSQVAMRC RCSSMHFLVA EWNEPSINFY KRRGASDLSS EEGWRLFKID KEYLLKMATE E.
溶解建议:
提供的人精脒/精胺乙酰转移酶1(SAT1)产品为过滤灭菌的无色溶液;其中人精脒/精胺乙酰转移酶1(SAT1)产品溶解于20mM Tris-HCl缓冲液(pH 8.0),10%甘油溶液中.
保存建议:
人精脒/精胺乙酰转移酶1(SAT1)溶液可以在4℃冷藏保存4周;如果想延长保存时间,建议分装(加载体蛋白如0.1% HSA或 BSA)后置于-18℃冻存.请避免反复冻融.
其他简介:
ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列,专注于蛋白(重组及合成)生产研发,其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子,生长因子,激素,信号蛋白,病毒抗原等近800种重组蛋白和100多种抗体,是世界上提供蛋白品种最多的公司之一,领先的生产工艺和规模使其可以提供毫克到克级蛋白,价格优于同类公司。绝大部分产品是天然成熟型蛋白,而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液,ProSpec-Tany绝大部分产品没有添加保护剂或盐,这就对工艺提出了更高的要求。同时,ProSpec-Tany绝大部分产品为冻干粉,因此易于运输和保存。
上海淳麦生物为ProSpec国内代理销售经销商,详细的产品信息请和我们联系:免费热线:4006815880 微信电话 13770640776
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重组人精脒/精胺乙酰转移酶1
¥700 - 1500






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