背景资料: LDHB is part of the lactate dehydrogenase family. LDHB is an oxidoreductase which catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. LDHB catalyzes the oxidation of hydroxybutyrate, and frequently called Hydroxybutyrate Dehydrogenase(HBD). The LDH family consists of thr人乳酸脱氢酶-B重组蛋白是在大肠杆菌中重组表达的,是一条单链、非糖基化的多肽链,包含有354个氨基酸(1-334 a.a.),分子量为38.8kDa.该人乳酸脱氢酶-B重组蛋白的N末端融合了一个20个氨基酸的His标签,该蛋白最终由标准的色谱技术纯化出. members, LDH-A, LDH-B and LDH-C. LDHs function as powerful markers for germ cell tumors.