产品英文名称: Recombinant Human Signaling Threshold Regulating Transmembrane Adaptor 1
英文简称: SIT1
中文名称: 重组人信号阈值调节跨膜接头蛋白1
背景资料: Signaling threshold-regulating transmembrane adapter 1 (SIT1) negatively regulates T-cell antigen receptor (TCR)-mediated signaling in T-cells. SIT1 is involved in positive selection of T-cells. SIT1 is specifically expressed in T- and B-cells. SIT1 is also present in plasma cells but not in germinal center B-cells (at protein level). SIT1 is expressed in T- and B-cell lymphoma.
产品描述: SIT1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 156 amino acids (62-196 a.a.) and having a molecular mass of 16.9kDa (Molecular weight on SDS-PAGE will appear higher).SIT1 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
来源宿主: 大肠杆菌中重组表达