重组人DDB1和CUL4关联因子7

产品英文名称：
Recombinant Human DCN1 Defective in Cullin NeDCN1-like protein 2 （DCUN1D2） which contains one DCUN1 domain and 1 UBA-like domain， may have a role in the neddylation of cullins which regulate SCF-type ubiquitin ligase complexes. The gene encoding Dcun1D2 is located on human chromosome 13. Chromosome 13 contains major tumor suppressor genes， including BRCA2 and RB1， which are linked with breast cancer susceptibility and retinoblastoma， respectively.ylation 1 Domain Containing 2

英文简称:
DCUN1D2

中文名称:
重组人缺陷于清选蛋白neDCN1-like protein 2 （DCUN1D2） which contains one DCUN1 domain and 1 UBA-like domain， may have a role in the neddylation of cullins which regulate SCF-type ubiquitin ligase complexes. The gene encoding Dcun1D2 is located on human chromosome 13. Chromosome 13 contains major tumor suppressor genes， including BRCA2 and RB1， which are linked with breast cancer susceptibility and retinoblastoma， respectively.ylation蛋白 1 域含2

背景资料:
DCN1-like protein 2 （DCUN1D2） which contains one DCUN1 domain and 1 UBA-like domain， may have a role in the neddylation of cullins which regulate SCF-type ubiquitin ligase complexes. The gene encoding Dcun1D2 is located on human chromosome 13. Chromosome 13 contains major tumor suppressor genes， including BRCA2 and RB1， which are linked with breast cancer susceptibility and retinoblastoma， respectively.

产品描述:
DCUN1D2 Human Recombinant produced in E.Coli is a single， non-glycosylated polypeptide chain containing 279 amino acids （1-259 a.a.） and having a molecular mass of 32.3kDa. DCUN1D2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
来源宿主:
大肠杆菌中重组表达

序列:
MGSSHHHHHH SSGLVPRGSH MHKLKSSQKD KVRQFMACTQ AGERTAIYCL TQNEWRLDEA TDSFFQNPDS LHRESMRNAV DKKKLERLYG RYKDPQDENK IGVDGIQQFC DDLSLDPASI SVLVIAWKFR AATQCEFSRK EFLDGMTELG CDSMEKLKAL LPRLEQELKD TAKFKDFYQF TFTFAKNPGQ KGLDLEMAVA YWKLVLSGRF KFLDLWNTFL MEHHKRSIPR DTWNLLLDFG NMIADDMSNY DEEGAWPVLI DDFVEYARPV VTGGKRSLF.

溶解建议:
提供的重组人缺陷于清选蛋白neddylation蛋白 1 域含2产品形式为经无菌过滤处理的无色溶液.

保存建议：
重组人缺陷于清选蛋白neddylation蛋白 1 域含2产品在4℃保存请2 - 4周内将使用；-20℃可长期保存.产品若长期保存，建议添加载体蛋白（0.1% HSA或BSA）.避免反复冻融.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。