重组人膜泡蛋白分类28

产品英文名称：
Bovine Vimentin

英文简称:
bVimentin

中文名称:
牛波形蛋白

背景资料:
Vimentin expression in human malignant glioma cells depends on cellular density， algorithms of drug delivery and chemo/radio treatment. Vimentin and detyrosinated microtubules provide structural support for the extensive microtentacles observed in detached tumor cells and a mechanism to promote successful metastatic spread. Primary colorectal carcinomas display aberrant expression of vimentin， and have activated Notch and TGFbeta signaling pathways. Vimentin is a strong arterial substrate for transglutaminases. Transglutaminase-mediated vimentin dimerization results in a novel unifying pathway by which vasodilatory and remodeling responses may be regulated. Ablation of vimentin expression inhibits migration and invasion of colon and breast cancer cell lines. Vimentin is the main intermediate filament protein in mesenchymal cells and is therefore of value in the di牛晶状体组织中提取纯化erential diagnosis of undi牛晶状体组织中提取纯化erentiated neoplasms.

产品描述:
Bovine Vimentin protein produced in Bovine Lens， having a molecular weight of 57 kDa.
来源宿主:
牛晶状体组织中提取纯化

序列:


溶解建议:
Sterile Filtered White lyophilized （freeze-dried） powder. The protein （1mg/ml） was lyophilized from a 1mg/ml solution containing 10mM sodium phosphate pH 7.5， 6M urea， 2mM DTT， 1mM EDTA and 10mM methylammonium chloride.It is recommended to reconstitute the Bovine Vimentin in sterile 18MΩ-cm H2O not less than 100ug/ml， which can then be further diluted to other aqueous solutions.

保存建议：
It is recommended to reconstitute the Bovine Vimentin in sterile 18MΩ-cm H2O not less than 100ug/ml， which can then be further diluted to other aqueous solutions.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。