产品英文名称: Recombinant Human Tyrosyl-DNA Phosphodiesterase 2
英文简称: TDP2
中文名称: 重组人酪氨酰DNA磷酸二酯酶2
背景资料: Tyrosyl-DNA Phosphodiesterase 2(TDP2), belongs to the CCR4/nocturin family of divalent cation-dependent phosphodiesterases.TDP2 associates with CD40, tumor necrosis factor(TNF) receptor-75 and TNF receptor associated factors(TRAFs), and inhibits nuclear factor-kappa-B activation. TDP2 is characterized by similar sequence and structure as APE1 endonuclease, which participates in DNA repair and the activation of transcription factors.
产品描述: TDP2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 385 amino acids(1-362) and having a molecular mass of 43.3kDa. TDP2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
来源宿主: 大肠杆菌中重组表达