重组HIV-1 p24蛋白

产品英文名称：
Recombinant Human SplSYK Human Recombinant full length protein （1-635 aa） produced in HEK 293 cells with an N-terminal His-Flag tag， having a molecular weight of 74.25kDa. Human SYK is purified by proprietary chromatographic techniques.n Tyrosine Kinase

英文简称:
SYK

中文名称:
重组人脾酪氨酸激酶

背景资料:
SplSYK Human Recombinant full length protein （1-635 aa） produced in HEK 293 cells with an N-terminal His-Flag tag， having a molecular weight of 74.25kDa. Human SYK is purified by proprietary chromatographic techniques.n Tyrosine Kinase （SYK） belongs to the family of non-receptor type Tyr protein kinases. The SYK protein is extensively expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events which mediate diverse cellular responses， including proliferation， diHEK293人胚肾上皮细胞中重组表达erentiation， and phagocytosis. SYK is considered to be a modulator of epithelial cell growth and a likely tumor suppressor in human breast carcinomas. SYK is a positive eHEK293人胚肾上皮细胞中重组表达ector of BCR-stimulated responses. SYK connects the B-cell antigen receptor （BCR） to the utilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway， when not phosphorylated on tyrosines of the linker region， or through a phospholipase C-gamma-dependent pathway， when phosphorylated on Tyr-348 and Tyr-352. Therefore the diHEK293人胚肾上皮细胞中重组表达erential phosphorylation of Syk can define the pathway by which BCR is coupled to the regulation of intracellular calcium ion （By similarity）. SYK also phosphorylates USP25 and regulates its intracellular levels.

产品描述:
SYK Human Recombinant full length protein （1-635 aa） produced in HEK 293 cells with an N-terminal His-Flag tag， having a molecular weight of 74.25kDa. Human SYK is purified by proprietary chromatographic techniques.
来源宿主:
HEK293人胚肾上皮细胞中重组表达

序列:
MHHHHHHDYKDDDDKKLMASSGMADSANHLPFFFGNITREEAEDYLVQGGMSDGL YLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTYAIAGGRTHASPADLCHYHSQES DGLVCLLKKPFNRPQGVQPKTGPFEDLKENLIREYVKQTWNLQGQALEQAIISQKPQL EKLIATTAHEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSYALCLLHEGKV LHYRIDKDKTGKLSIPEGKKFDTLWQLVEHYSYKADGLLRVLTVPCQKIGTQGNVNFG GRPQLPGSHPATWSAGGIISRIKSYSFPKPGHRKSSPAQGNRQESTVSFNPYEPELA PWAADKGPQREALPMDTEVYESPYADPEEIRPKEVYLDRKLLTLEDKELGSGNFGTV KKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRMIGICEAES WMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARN VLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVW SFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWT YDVENRPGFAAVELRLRNYYYDVVN.

溶解建议:
提供的重组人脾酪氨酸激酶产品形式为无菌的无色溶液.

保存建议：
建议将重组人脾酪氨酸激酶产品整瓶保存于4℃可保存2-4周. 长期保存，请置于-20℃.请避免反复冻融.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。