重组B19病毒壳蛋白VP1/VP2

产品英文名称：
Recombinant Human Vascular Endothelial Growth Factor receptor-1 His Tag

英文简称:
FLT1 His

中文名称:
重组人血管内皮生长因子受体-1，His标签

背景资料:
Endothelial cells express thrFLT1 Human Recombinant produced in E.Coli is single， a non-glycosylated， Polypeptide chain containing 298 amino acids fragment （31-328） corresponding to the IgG like domains 1-3 from the mature soluble FLT1 protein， having a total molecular mass of 43kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. The FLT1 His is purified by proprietary chromatographic techniques. di大肠杆菌中重组表达erent vascular endothelial growth factor （VEGF） receptors， belonging to the family of receptor tyrosine kinases （RTKs）. They are named VEGFR-1 （Flt-1）， VEGFR-2 （KDR/Flk-1）， VEGFR-3 （Flt-4）. Their expression is almost exclusively restricted to endothelial cells， but VEGFR-1 can also be found on monocytes， dendritic cells and on trophoblast cells. The flt-1 gene was first described in 1990. The receptor contains seven immunoglobulin-like extracellular domains， a single transmembrane region and an intracellular splited tyrosine kinase domain. Compared to VEGFR-2 the Flt-1 receptor has a higher a大肠杆菌中重组表达inity for VEGF but a weaker signaling activity. VEGFR-1 thus leads not to proliferation of endothelial cells， but mediates signals for di大肠杆菌中重组表达erentiation. Interestingly a naturally occuring soluble variant of VEGFR-1 （sVEGFR-1） was found in HUVE supernatants in 1996， which is generated by alternative splicing of the flt-1 mRNA. The biological functions of sVEGFR-1 still are not clear， but it sFLT1 Human Recombinant produced in E.Coli is single， a non-glycosylated， Polypeptide chain containing 298 amino acids fragment （31-328） corresponding to the IgG like domains 1-3 from the mature soluble FLT1 protein， having a total molecular mass of 43kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. The FLT1 His is purified by proprietary chromatographic techniques.ms to be an endogenous regulator of angiogenesis， binding VEGF with the same a大肠杆菌中重组表达inity as the full-length receptor.

产品描述:
FLT1 Human Recombinant produced in E.Coli is single， a non-glycosylated， Polypeptide chain containing 298 amino acids fragment （31-328） corresponding to the IgG like domains 1-3 from the mature soluble FLT1 protein， having a total molecular mass of 43kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. The FLT1 His is purified by proprietary chromatographic techniques.
来源宿主:
大肠杆菌中重组表达

序列:


溶解建议:
提供的人血管内皮生长因子受体-1，His标签（FLT1 His）产品为过滤灭菌的透明溶液；其中人血管内皮生长因子受体-1，His标签（FLT1 His）产品溶解于1x PBS，50%甘油溶液中.

保存建议：
人血管内皮生长因子受体-1，His标签（FLT1 His）溶液可以在4℃冷藏保存2-4周；如果想延长保存时间，建议分装后置于-20℃冻存.请避免反复冻融.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。