产品英文名称: Recombinant Human Macrophage Inflammatory protein-5 (CCL15) 68 a.a
英文简称: MIP 5 (68 a.a.)
中文名称: 重组人巨噬细胞炎性蛋白5(CCL15) 68 a.a
背景资料: CCL15, a new human CC chemokine, was isolated from a human fetal spl重组人巨噬细胞炎性蛋白5(CCL15) 68 a.a是在大肠杆菌中重组表达的,是一条非糖基化的多肽链,包含有 68 个氨基酸 分子量为 7.4kDa. The MIP5 最终由标准的色谱技术纯化获得..n cDNA library. CCL15 cDNA encodes a predicted 113 amino acid (aa) protein containing a putative signal peptide of 21 amino acids that is cleaved to generate a 92 aa residue mature protein. Within the CC family members, human CCL15 shares 45%, 44%, 35%, and 30% aa homology with mouse C10, human MPIF-1, human HCC-1, and mouse MIP-1?, respectively. The gene for MIP-5 is found on chromosome 17 where the genes for most of the human CC chemokines are located. Human CCL15 is expressed in T and B lymphocytes, NK cells, monocytes and monocyte-derived dendritic cells. Human MIP-5 is chemotactic for T cells and monocytes and has b重组人巨噬细胞炎性蛋白5(CCL15) 68 a.a是在大肠杆菌中重组表达的,是一条非糖基化的多肽链,包含有 68 个氨基酸 分子量为 7.4kDa. The MIP5 最终由标准的色谱技术纯化获得..n shown to induce calcium flux in human CCR-1-transfected cells.