背景资料: GLO1 is involved in the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. GLO1 is linked to HLA and is localized to 6p21.3-p21.1, betw人乙二醛酶-I重组蛋白是在大肠杆菌中重组表达的,是一条单链、非糖基化的多肽链,包含有184个氨基酸,分子量为20.7kDa.该人乙二醛酶-I重组蛋白最终由标准的色谱技术纯化出.n HLA and the centromere. GLO1 enzyme is ubundantly expressed and present in numerous tumor cell lines, in which its concentration is often upregulated ubiquitisly. GLO1 is a major susceptible gene for autism in an ethnic Chinese population from Taiwan. GLO1 might be involved in the pathophysiology of mood disorders. GLO1 plays a role in the pathophysiology of mood disorders. Overexpression of GLO1 is associated with kidney tumor.