MAP1LC3B

产品英文名称：
Recombinant Human Tubulin Folding Cofactor A

英文简称:
TBCA

中文名称:
重组人微管蛋白折叠辅助因子A

背景资料:
TBCA is a tubulin-folding protein which is involved in the early step of the tubulin folding pathway. TBCA is one of four proteins （cofactors A， D， E， and C） implicated in the pathway directing to properly folded beta-tubulin from folding intermediates. Cofactors A and D are thought to be a factor in capturing and stabilizing beta-tubulin in a quasi-native confirmation. TBCA is crucial for cell viability， if reduced it causes a decrease in the amount of soluble tubulin， alterations in microtubules and G1 cell cycle arrest. Cofactor E attaches to the cofactor D-tubulin complex， afterward， interaction with cofactor C triMADPRVRQIK IKTGVVKRLV KEKVMYEKEA KQQEEKIEKM RAEDGENYDI KKQAEILQES RMMIPDCQRR LEAAYLDLQR ILENEKDLEE AEEYKEARLV LDSVKLEA.ers the release of tubulin polypeptides that are committed to the native state.

产品描述:
TBCA Human Recombinant produced in E.Coli is a single， non-glycosylated， polypeptide chain containing 108 amino acids （1-108 a.a.） and having a molecular mass of 12.8 kDa. The TBCA is purified by proprietary chromatographic techniques.
来源宿主:
大肠杆菌中重组表达

序列:
MADPRVRQIK IKTGVVKRLV KEKVMYEKEA KQQEEKIEKM RAEDGENYDI KKQAEILQES RMMIPDCQRR LEAAYLDLQR ILENEKDLEE AEEYKEARLV LDSVKLEA.

溶解建议:
Sterile Filtered colorless solution. The TBCA solution contains 20mM Tris-HCl buffer pH 7.5， 1mM DTT and 10% glycerol.

保存建议：
TBCA although stable 4℃ for 4 weeks， should be stored desiccated below -18℃. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。