HIV-1 p24 gag

产品英文名称：
Recombinant Hepatitis B Virus e-Antigen

英文简称:
HBeAg

中文名称:
重组丙型肝炎病毒e抗原

背景资料:
Hepatitis B virus is the main cause for human liver disease， chronic infection frequently causes liver cancer and cirrhosis. The HBV core gene codes 2 distinct protein products， a 21.5-kDa protein being assembled to form nucleocapsid particles designated HBcAg， which wraps the viral DNA as well as the viral polymerase and RNase H， and a precore protein， designated as HBeAg， which is directly to the endoplasmic reticulum， processed at N- and C-terminally and secreted as non-particulate e-anitgen （HBeAg）. The pre-core protein contains an extra 29 N-terminal amino acids， serving as a signal peptide to direct the nascent polypeptide into secretory pathway. After the secretion， mature HBeAg is deleted at the residue 149 C-terminally and retains 10 precore residues N-terminally. HBcAg and HBeAg are distinctly recognized by antibodies but highly cross-reactive at the T-cell level. The e antigen is found in the circulation， it is found during the active HBV infection， positive result indicates the risk for contagiousness， and is also used as indicator for the e大肠杆菌中重组表达ectiveness of HBV treatment. Positive anti-HBeAg specifies an active stage of acute HBV infection that is in its final stages， the risk for contagiousness is dramatically reduced.

产品描述:
Recombinant e antigen consists of HBV e immunodominant region containing 10 precore residues at its N-terminus and 1-149 residues from the end of precore to its C-terminus. HBV e-Antigen was expressed from E. Coli， the purified recombinant core antigen can be used for ELISA assay and Western blot for clinical study and research.
来源宿主:
大肠杆菌中重组表达

序列:


溶解建议:
提供的重组丙型肝炎病毒e抗原产品为溶液形式.该产品已溶解在含2M 尿素的20mM 磷酸钠缓冲液.

保存建议：
Five years frozen. One month in solution at room temperature.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。