Anti-KCNN1 antibody

Anti-KCNN1 antibody

Cat. No.     JC264331       
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-KCNN1 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human KCNN1
Reactivity                 Human, Mouse, Rat
Content                     1.56 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 KCNN1
Full name                 potassium calcium-activated channel subfamily N member 1
Synonyms    SK1; hSK1; SKCA1; KCa2.1
Swissprot    Q92952

Target Background
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes.

Anti-KCNN1 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 50-300    Predicted cell location: Cytoplasm
Positive control: Human cervical cancer
Recommended dilution: 50-300