VEGF Receptor 1

产品名称：VEGF Receptor 1 抗体（pTyr1048）：偶联ATTO 633-VEGF Receptor 1 Antibody (pTyr1048): ATTO 633

 

产品货号：SPC-1095D-A633

 

产品规格：100ul

 

应用类型：WB | AM

 

 

保存建议：VEGF Receptor 1 抗体（pTyr1048）：偶联ATTO 633-VEGF Receptor 1 Antibody (pTyr1048): ATTO 633厂家推荐蓝冰运输。收到产品后建议保存于-20ºC。

 

背景资料：FLT1 is a receptor-tyrosine kinase that is activated upon binding with VEGF-A, VEGF-B and PGF. It plays an important role in the development of embryonic vasculature, and as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. However, it can promote PGF-mediated endothelial cell proliferation, survival and angiogenesis in adults, although this seems to be cell-type specific. It also contributes to cancer cell survival, proliferation, migration, and invasion, as well as tumour angiogenesis, metastasis, and recruitment of tumour-infiltrating macrophages. It has a very high affinity for VEGF-A and may function as a negative regulator of VEGF-A signalling by limiting the amount of free VEGF-A and preventing its binding to KDR. Isoforms lacking a transmembrane domain may function as decoy receptors for VEGF-A. Furthermore, it mediates phosphorylation of PI3K, leading to activation of the downstream signalling pathway, as well as mediating the activation of the MAPK signalling pathway, and of the Akt/PKB signalling pathway.

 

点击：VEGF Receptor 1 抗体（pTyr1048）：偶联ATTO 633-VEGF Receptor 1 Antibody (pTyr1048): ATTO 633查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-868垂询StressMarq中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看每日生物评论网站。

 

关键词：VEGF Receptor 1 Antibody (pTyr1048): ATTO 633，VEGF Receptor 1 抗体（pTyr1048）：偶联ATTO 633，VEGF Receptor 1