Product overview
Description Anti-EN2 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human EN2
Reactivity Human, Mouse
Content 0.96 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-EN2 antibody Target information
Symbol EN2
Full name engrailed homeobox 2
Synonyms
Swissprot P19622
Target Background
Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.
Anti-EN2 antibody Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human ovarian cancer
Recommended dilution: 30-150