Product overview
Description Anti-CCR4 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human CCR4
Reactivity Human, Mouse
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CCR4
Full name chemokine (C-C motif) receptor 4
Synonyms CKR4; K5-5; CD194; CMKBR4; ChemR13; CC-CKR-4; HGCN:14099
Swissprot P51679
Target Background
The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
Anti-CCR4 antibody Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human tonsil
Recommended dilution: 20-100 Predicted cell location: Cytoplasm
Positive control: Human cervical cancer
Recommended dilution: 20-100