Product overview
Description Anti-KLRC3 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human KLRC3
Reactivity Human
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol KLRC3
Full name killer cell lectin-like receptor subfamily C, member 3
Synonyms NKG2E; NKG2-E
Swissprot Q07444
Target Background
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
Anti-KLRC3 antibody Applications
Immunohistochemistry
Predicted cell location: Cell membrane
Positive control: Human tonsil
Recommended dilution: 25-100 Predicted cell location: Cell membrane
Positive control: Human cervical cancer
Recommended dilution: 25-100