Product overview
Description Anti-GANAB rabbit polyclonal antibody
Applications ELISA, WB
Immunogen Synthetic peptide of human GANAB
Reactivity Human, Mouse
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol GANAB
Full name glucosidase, alpha; neutral AB
Synonyms G2AN; GLUII
Swissprot Q14697
Target Background
Trimming of glucoses from N-linked core glycans on newly synthesized glycoproteins occurs sequentially through the action of Glucosidases I and II in the endoplasmic reticulum (ER). Glucosidase II is an ER-localized enzyme that contains a and b subunits (Glucosidase IIa and Glucosidase IIb) which form a defined heterodimeric complex. Glucosidase IIa is the catalyitc core of the enzyme and can function independently of the b subunit. The sequence of Glucosidase IIb encodes protein rich in glutamic and aspartic acid with a putative ER retention signal (HDEL) at the C-terminus.
Anti-GANAB antibody Applications
Western blotting
Predicted band size:107 kDa
Positive control:Hela,A431,Hepg-2,293T and Raji cell
Recommended dilution: 200-1000