Anti-CXCR4 antibody

Anti-CXCR4 antibody

Cat. No.   JC262693
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-CXCR4 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human CXCR4
Reactivity                 Human, Mouse, Rat
Content                     0.6 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 CXCR4
Full name                 chemokine (C-X-C motif) receptor 4
Synonyms    FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LAP-3; LESTR; NPY3R; NPYRL; WHIMS; HSY3RR; NPYY3R; D2S201E
Swissprot    P61073

Target Background
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Anti-CXCR4 antibody
Applications
Immunohistochemistry
Predicted cell location: Cell membrane
Positive control: Human liver cancer
Recommended dilution: 25-100    Predicted cell location: Cell membrane
Positive control: Human esophagus cancer
Recommended dilution: 25-100