Product overview
Description Anti-SPDL1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human SPDL1
Reactivity Human
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol SPDL1
Full name spindle apparatus coiled-coil protein 1
Synonyms CCDC99
Swissprot Q96EA4
Target Background
Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.
Anti-SPDL1 antibody Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 25-100 Predicted cell location: Cytoplasm
Positive control: Human esophagus cancer
Recommended dilution: 25-100