Anti-MET antibody

Anti-MET antibody

Cat. No.     JC260981
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-MET rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human MET
Reactivity                 Human, Mouse, Rat
Content                     0.5 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 MET
Full name                 MET proto-oncogene, receptor tyrosine kinase
Synonyms    HGFR; AUTS9; RCCP2; c-Met
Swissprot    P08581

Target Background
The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene.

Anti-MET antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm and Nucleus
Positive control: Human esophagus cancer
Recommended dilution: 25-100