Product overview
Description Anti-BAZ1A rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human BAZ1A
Reactivity Human, Mouse
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol BAZ1A
Full name bromodomain adjacent to zinc finger domain, 1A
Synonyms ACF1; WALp1; hACF1; WCRF180
Swissprot Q9NRL2
Target Background
Bromodomain adjacent to zinc finger domain protein 1A is a protein that in humans is encoded by the BAZ1A gene. Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase.