Product overview
Description Anti-PER3 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human PER3
Reactivity Human, Mouse, Rat
Content 1.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-PER3 antibody Target information
Symbol PER3
Full name period circadian regulator 3
Synonyms GIG13; FASPS3
Swissprot P56645
Target Background
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene.
Anti-PER3 antibody Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human tonsil
Recommended dilution: 50-300 Predicted cell location: Cytoplasm
Positive control: Human esophagus cancer
Recommended dilution: 50-300