Anti-ARMC8 antibody

Anti-ARMC8 antibody

Cat. No.    JC224914 
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-ARMC8 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human ARMC8
Reactivity                 Human, Mouse
Content                     0.66 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 ARMC8
Full name                 armadillo repeat containing 8
Synonyms    GID5; VID28; S863-2; HSPC056
Swissprot    Q8IUR7

Target Background
The armadillo (ARM) repeat family of proteins are related to the Drosophila melanogaster armadillo protein, a protein essential for wingless signal transduction. ARM proteins are involved in a variety of processes such as cell migration, cell proliferation, tissue maintenance and tumorigenesis, and they also function in signal transduction and the maintenance of overall cell structure. ARMC8 (armadillo repeat containing 8), also known as S863-2, is a 673 amino acid protein that contains 14 ARM repeats, suggesting a role in signal transduction events throughout the cell. Six isoforms of ARMC8 are expressed due to alternative splicing events. The gene encoding ARMC8 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.

Anti-ARMC8 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm and Nucleus
Positive control: Human esophagus cancer
Recommended dilution: 40-200    Predicted cell location: Cytoplasm and Nucleus
Positive control: Human thyroid cancer
Recommended dilution: 40-200