Anti-CCDC181 antibody

Anti-CCDC181 antibody

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  • 询价
  • gelatins
  • JC224334
  • 进口/国产
  • 2025年12月11日
  • ELISA, WB
  • Rabbit
  • 人/动物/植物
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    • 详细信息
    • 技术资料
    • 供应商

      上海机纯实业有限公司

    • 库存

      大量

    • 克隆性

      多克隆

    • 保质期

      12个月

    • 抗体英文名

      Anti-CCDC181 antibody

    • 宿主

      Rabbit

    • 适应物种

      人/动物/植物

    • 应用范围

      ELISA, WB

    • 浓度

      0.5 mg/ml

    • 保存条件

      -20°C

    • 规格

      25 μl/100 μl/200 μl

    Anti-CCDC181 antibody

    Cat. No.     JC224334 
    Package    25 μl/100 μl/200 μl
    Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

    Product overview
    Description                   Anti-CCDC181 rabbit polyclonal antibody
    Applications        ELISA, WB, IHC 
    Immunogen               Fusion protein of human CCDC181
    Reactivity                 Human, Mouse
    Content                     0.5 mg/ml
    Host species               Rabbit
    Ig class                  Immunogen-specific rabbit IgG
    Purification                 Antigen affinity purification
    Anti-CCDC181 antibody
    Target information
    Symbol                 CCDC181
    Full name                 coiled-coil domain containing 181
    Synonyms    C1orf114
    Swissprot    Q5TID7

    Target Background
    CCDC181, also known as C1orf114, chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf114 gene product has been provisionally designated C1orf114 pending further characterization.

    Anti-CCDC181 antibody
    Applications
    Immunohistochemistry
    Predicted cell location: Nucleus
    Positive control: Human lung cancer
    Recommended dilution: 25-100    Predicted cell location: Nucleus
    Positive control: Human prostate cancer
    Recommended dilution: 25-100

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