Anti-ZUFSP antibody

Anti-ZUFSP antibody

Cat. No.     JC224052
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-ZUFSP rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Fusion protein of human ZUFSP
Reactivity                 Human, Mouse, Rat
Content                     0.7 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 ZUFSP
Full name                 zinc finger with UFM1-specific peptidase domain
Synonyms    C6orf113; dJ412I7.3
Swissprot    Q96AP4

Target Background
Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6.

Applications
Immunohistochemistry
Predicted cell location: Nucleus and Cytoplasm
Positive control: Human gastric cancer
Recommended dilution: 25-100    Predicted cell location: Nucleus and Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 25-100