- 询价
- gelatins
- JC220313
- 进口/国产
- 2025年07月07日
- ELISA, WB
- Rabbit
- 人/动物/植物
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海机纯实业有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
12个月
- 抗体英文名：
Anti-BIN1 antibody
- 宿主：
Rabbit
- 适应物种：
人/动物/植物
- 应用范围：
ELISA, WB
- 浓度：
0.1 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Cat. No. JC220313
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-BIN1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human BIN1
Reactivity Human
Content 0.1 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-BIN1 antibody
Target information
Symbol BIN1
Full name bridging integrator 1
Synonyms AMPH2; AMPHL; SH3P9
Swissprot O00499
Target Background
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.
Anti-BIN1 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 50-200 Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 50-200
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