Anti-GMFB antibody

Anti-GMFB antibody

Cat. No.     JC223834
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-GMFB rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human GMFB
Reactivity                 Human, Mouse, Rat
Content                     0.7 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 GMFB
Full name                 glia maturation factor, beta
Synonyms    GMF
Swissprot    P60983

Target Background
This protein, which is phosphorylated following phorbol ester stimulation, is important for the nervous system. It causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. Overexpression of GMF in astrocytes has been shown to enhance brain-derived neurotrohic factor (BDNF) production. GMF expression is increased by exercise, and the protein is crucial for exercise-induction of BDNF. Through BDNF production, GMF appears to play a role in neuroprotection. In thymoma, T-cell development is maintained by GMF-∫ being produced by the tumor cells.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human prostate cancer
Recommended dilution: 25-100